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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUMA1 All Species: 10
Human Site: T1677 Identified Species: 44
UniProt: Q14980 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14980 NP_006176.2 2115 238260 T1677 E Q T C R H L T A Q V R S L E
Chimpanzee Pan troglodytes Q8HZ60 782 88641 S368 Q L K G Q V A S L Q E K V T S
Rhesus Macaque Macaca mulatta XP_001114092 2118 238470 T1677 E Q T C R H L T A Q V R S L E
Dog Lupus familis XP_542331 1681 189932 H1267 L R A K A Q D H S K A E D E W
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001081559 2253 256778 S1765 E Q N C K N L S N R V R S L E
Zebra Danio Brachydanio rerio XP_701145 2099 242274 K1623 Q E K E V Q M K H E L S V L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.1 95.4 67 N.A. N.A. N.A. N.A. N.A. N.A. 38.4 22 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 28.8 97 71.8 N.A. N.A. N.A. N.A. N.A. N.A. 59.7 44.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 0 N.A. N.A. N.A. N.A. N.A. N.A. 60 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 20 N.A. N.A. N.A. N.A. N.A. N.A. 86.6 46.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 17 0 17 0 34 0 17 0 0 0 0 % A
% Cys: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 17 0 0 0 0 0 17 0 0 % D
% Glu: 50 17 0 17 0 0 0 0 0 17 17 17 0 17 67 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 34 0 17 17 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 34 17 17 0 0 17 0 17 0 17 0 0 0 % K
% Leu: 17 17 0 0 0 0 50 0 17 0 17 0 0 67 0 % L
% Met: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 0 0 17 0 0 17 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 34 50 0 0 17 34 0 0 0 50 0 0 0 0 0 % Q
% Arg: 0 17 0 0 34 0 0 0 0 17 0 50 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 34 17 0 0 17 50 0 17 % S
% Thr: 0 0 34 0 0 0 0 34 0 0 0 0 0 17 0 % T
% Val: 0 0 0 0 17 17 0 0 0 0 50 0 34 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _